Propecia is a drug often used to treat hair loss. It is one of the few medications approved by the upper bodies of health, and that proved to be effective. It is recommended that only men take it because on women it can affect pregnancy.
What makes it work?
The active ingredient Finasteride prospectus is an antiandrogen. It was approved for the first time in 1992 in the form of Proscar to treat the problem of prostate enlargement. Subsequent studies have shown that small amounts of finasteride is able to create reversing hair loss.
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Finasteride acts as inhibitor of the enzyme 5 – alpha reductase, which unites testosterone to form DHT. By blocking the enzyme in your body GHT will drop and it will not add to the scalp.
If you choose to buy propecia online, then you should know that it’s used solely for the treatment of androgenic alopecia. Androgenic Alopecia, also called seborrheic alopecia or male pattern alopecia (early male baldness) and diffuse alopecia are the most common.
It first appears around the age of 20 years and has an occurrence rate of about 80 % in men over 70 years.
After stretching, is of several types : about 20 years appears type I (fronto – temporal region) about 30 years Type II (crown, vertex) from 40 type III (forehead) 50 years nearly half of the region ‘s forehead alopecia, alopecia area stretching from vertex (type IV) After 55 years, there may be so-called “Hippocratic balding” (type V), leaving hair only on the edge.
Retrospective studies on patients with alopecia androgenogenetica men and women have shown that depression is more common in women, and anxiety, aggressiveness or hostility are more common in men. Specific psychotropic treatments have improved in 80% of cases the mental symptoms of patients studied. Choose to buy propecia online and these symptoms will disappear. Scalp seborrheic area is frequently affected by descuamation dry (pityriasis simplex) of a exudation fatty deposits sometimes adherent (seborrheic eczema). Etiopathogenesis includes 3 factors: genetic inheritance, androgen and seborrhea.
These characters have been demonstrated mainly in men, although this type of alopecia is commonly present.
In men, androgen alopecia responds well in clinically these characteristics, while in women, thinning hair is exceptional in this unique location, even if there is a prevalent with age.
Male androgen alopecia
Today, it is recognized that with androgen alopecia there is an increase in activity 5 – alpha reductase, the enzyme that converts free testosterone into dihydrotestosterone (DHT). It is 20 times more active than the follicles filosebace in testicular hormone.
The intensity of expression of these genes does not influence the presence or absence of alopecia. So we can assume that 5 – alpha reductase hyperactivity is a secondary phenomenon and not primary (possibly secondary to an increase in androgens or an androgen receptor hypersensitivity).
The mechanism by which increasing local DHT destroys the hair follicle has not been shown, so it is assumed that there is an inhibition of cell proliferation in the papilla and a vascular phenomenon by inhibiting local production of vascular endothelial growth factor (VEGF).
Increased activity of 5 alpha and the reduction in androgen is genetically determined. Male androgen alopecia is associated with insulin resistance and increased risk of polycystic ovaries in the female descendants.
This explains hormondependenta demonstrated efficacy of 5-alpha reduces inhibitors (e.g. finasteride reduces type 2 inhibitor, but the specificity of partial disappears at the doses used).